Please find below annual lists of the publications that took advantage of the services provided by Bioinformatics Center.

Karttunen, J.; Heiskanen, M.; Lipponen, A.; Poulsen, D.; Pitkänen, A. Extracellular Vesicles as Diagnostics and Therapeutics for Structural Epilepsies, Int. J. Mol. Sci. 2019, 20(6), 1259; https://doi.org/10.3390/ijms20061259

Failli M, Paananen J, Fortino V. Prioritizing target-disease associations with novel safety and efficacy scoring methods, Sci Rep 2019, https://doi.org/10.1038/s41598-019-46293-7

Timonen O, Särkkä M, Fülöp T, Mattsson A, Kekäläinen J, Paananen J, Varanto: variant enrichment analysis and annotation, Bioinformatics 2019, https://doi.org/10.1093/bioinformatics/btz046

Lipponen A, Natunen T, Hujo M, Ciszek R, Hämäläinen E, Tohka J, Hiltunen M, Paananen J, Poulsen D, Kansanen E, Ndode-Ekane XE, Levonen AL, Pitkänen A, In Vitro and In Vivo Pipeline for Validation of Disease-Modifying Effects of Systems Biology-Derived Network Treatments for Traumatic Brain Injury—Lessons Learned, Int. J. Mol. Sci. 2019, https://doi.org/10.3390/ijms20215395

Pölönen P, Mehtonen J, Lin J, Liuksiala T, Häyrynen S, Teppo S, Mäkinen A, Kumar A, Malani D, Pohjolainen V, Porkka K, Heckman CA, May P, Hautamäki V, Granberg K, Lohi O, Nykter M, Heinäniemi M: Hemap: An interactive online resource for characterizing molecular phenotypes across hematologic malignancies, Cancer Research 2019, https://doi.org/10.1158/0008-5472.CAN-18-2970

Mehtonen J, Pölönen P, Häyrynen S, Lin J, Liuksiala T, Granberg K, Lohi O, Hautamäki V, Nykter M, Heinäniemi M. Data-driven characterization of molecular phenotypes across heterogenous sample collections, Nucleic Acids Research 2019, https://doi.org/10.1093/nar/gkz281

Chen X, Ayala I, Shannon C, Fourcaudot M, Acharya NK, Jenkinson CP, Heikkinen S, Norton L. The Diabetes Gene and Wnt Pathway Effector TCF7L2 Regulates Adipocyte Development and Function, Diabetes 2018, https://doi.org/10.2337/db17-0318.

Niskanen H, Tuszynska I, Zaborowski R, Heinäniemi M, Ylä-Herttuala S, Wilczynski B, Kaikkonen MU.Endothelial cell differentiation is encompassed by changes in long range interactions between inactive chromatin regions Nucleic Acids Res. 2018, 10.1093/nar/gkx1214.

Lewis, JD, Evans, AC, Tohka J. T1 white/gray contrast as a predictor of chronological age, and an index of cognitive performance NeuroImage 2018, https://doi.org/10.1016/j.neuroimage.2018.02.050

Marttinen M, Paananen J, Neme A, Mitra V, Takalo M, Natunen T, Paldanius KMA, Mäkinen P, Bremang M, Kurki MI, Rauramaa T, Leinonen V, Soininen H, Haapasalo A, Pike I, Hiltunen M A multiomic approach to characterize the temporal sequence in Alzheimer's disease-related pathology, Neurobiol Dis. 2019, https://doi.org/10.1016/j.nbd.2018.12.009

Martiskainen H, Takalo M, Solomon A, Stančáková A, Marttinen M, Natunen T, Haapasalo A, Herukka SK, Kuusisto J, Soininen H, Kivipelto M, Laakso M, Hiltunen M. Decreased plasma C-reactive protein levels in APOE ε4 allele carriers, Ann Clin Transl Neurol. 2018. https://doi.org/10.1002/acn3.639.

Kaartokallio T, Utge S, Klemetti MM, Paananen J, Pulkki K, Romppanen J, Tikkanen I, Heinonen S, Kajantie E, Kere J, Kivinen K, Pouta A, Lakkisto P, Laivuori H. Fetal Microsatellite in the Heme Oxygenase 1 Promoter Is Associated With Severe and Early-Onset Preeclampsia , Hypertension 2018, https://doi.org/10.1161/HYPERTENSIONAHA.117.10425.

Paananen, J. Bioinformatics in the Identification of Novel Targets and Pathways in Neurodegenerative Diseases, Curr Genet Med Rep (2017) 5:15–21, https://doi.org/10.1007/s40142-017-0115-8